COVID-19 in Brazil: spatial risk, social vulnerability, human development, clinical manifestations and predictors of mortality - a retrospective study with data from 59 695 individuals.

Brazil ranks second in the number of confirmed cases of COVID-19 worldwide. In spite of this, coping measures differ throughout the national territory, as does the disease's impact on the population. This cross-sectional observational study, with 59 695 cases of COVID-19 registered in the state of Alagoas between March and August 2020, analysed clinical-epidemiological variables, incidence rate, mortality rate, case fatality rate (CFR) and the social indicators municipal human development index (MHDI) and social vulnerability index (SVI). Moran statistics and regression models were applied. Logistic regression analysis was applied to determine the predictors of death. The incidence rate was 1788.7/100 000 inhabitants; mortality rate was 48.0/100 000 and CFR was 2.7%. The highest incidence rates were observed in municipalities with better human development (overall MHDI (I = 0.1668; p = 0.002), education MHDI (I = 0.1649; p = 0.002) and income MHDI (I = 0.1880; p = 0.005)) and higher social vulnerability (overall SVI (I = 0.0599; p = 0.033)). CFR was associated with higher social vulnerability (SVI human capital (I = 0.0858; p = 0.004) and SVI urban infrastructure (I = 0.0985; p = 0.040)). Of the analysed cases, 55.4% were female; 2/3 were Black or Brown and the median age was 41 years. Among deaths, most were male (919; 57.4%) and elderly (1171; 73.1%). The predictors of death were male sex, advanced age and the presence of comorbidities. In Alagoas, Brazil, the disease has undergone a process of interiorisation and caused more deaths in poorer municipalities. The presence of comorbidities and advanced age were predictors of death.

Análise do perfil epidemiológico e tendência temporal dos acidentes graves de trabalho / Análisis del perfil epidemiológico y la tendencia temporal de accidentes de trabajo graves / Analysis of the epidemiological profile and temporal trend of serious occupational accidents

Objetivo analisar o perfil epidemiológico e a tendência temporal dos acidentes graves de trabalho no estado de Sergipe, no período de 2009 a 2015. Método estudo ecológico, descritivo, de série temporal, com base em dados secundários informados no Sistema de Informação de Agravos de Notificação. Resultados foram notificados 1.271 acidentes graves de trabalho com trabalhadores entre 16 e 65 anos de idade; os anos de 2011 (19,5%) e 2009 (15,6%) foram os de maior número de registros; 2011 (23,6%) e 2010 (19.9%) apresentaram maior incidência; 2014 e 2015 registraram as menores taxas. Perfil dos trabalhadores acidentados: sexo masculino (88,8%), entre 25 e 29 anos (17,1%), pardos (61,5%), ensino incompleto da 5ª a 8ª série (20,2%). Conclusão a análise do perfil epidemiológico e a tendência temporal dos acidentes graves de trabalho no estado de Sergipe revelou tendência geral decrescente no período analisado, ainda que fosse elevado o número de acidentes registrados.

Objetivo analizar el perfil epidemiológico y la tendencia temporal de los accidentes de trabajo graves en el estado de Sergipe, en el período comprendido entre 2009 y 2015. Método estudio ecológico, descriptivo, de series de tiempo, basado en datos secundarios reportados en el Sistema de Información de Agravios de Notificación. Resultados se reportaron 1.271 accidentes de trabajo graves con los trabajadores con edad entre 16 y 65 años; los años 2011 (19,5%) y 2009 (15,6%) fueron el mayor número de registros; 2011 (23,6%) y 2010 (19,9%) tuvieron una mayor incidencia; 2014 y 2015 registraron las tasas más bajas. El perfil de los trabajadores lesionados: varones (88,8%), entre 25 y 29 años (17,1%), pardos (61,5%), enseñanza incompleta del 5º a 8º grado (20,2%). Conclusión el análisis del perfil epidemiológico y la tendencia temporal de accidentes de trabajo graves en el estado de Sergipe mostró una tendencia decreciente en el período analizado, aunque el número de accidentes registrados fue elevado.

Objective to analyze the epidemiological profile and the temporal trend of serious occupational accidents in Sergipe, in the period from 2009 to 2015. Method ecological, descriptive, time-series study, based on secondary data reported on the Information System for Disease Notification. Results there were 1,271 reports of serious occupational accidents with workers aged between 16 and 65 years; the years 2011 (19.5%) and 2009 (15.6%) presented the highest number of records; 2011 (23.6%) and 2010 (19.9%) had the highest incidence; 2014 and 2015 recorded the lowest rates. Profile of injured workers: males (88.8%), between 25 and 29 years (17.1%), pardos (61.5%), incomplete education from 5 th to 8 th grade (20.2%). Conclusion the analysis of the epidemiological profile and the temporal trend of serious occupational accidents in the state of Sergipe showed decreasing trend in the analyzed period, although the number of accidents recorded was high.